Factors –455 G/A Genotype Mann-Whitney ANOVA GG n=89 GA/AA n=44 p-value p-value LAD atherosclerosis % (mean areas, SD)         Fatty 6.52 (6.97) 6.43 (5.65) 0.54 0.72 Fibrous 4.61 (5.84) 3.60 (3.46) 0.75 0.32 Complicated 1.52 (4.10) 0.98 (2.78) 0.36 0.35 Calcification 4.20 (7.99) 3.43 (5.12) 0.67 0.51 Abdominal Aorta Atherosclerosis (mean areas, SD) GG n=135 GA/AA n=55     Fatty 13.7 (8.95) 15.6 (13.2) 0.41 0.29 Fibrous 7.37 (4.81) 7.25 (5.61) 0.89 0.18 Complicated 8.21 (10.3) 8.74 (12.9) 0.76 0.99 Calcification 5.47 (6.73) 4.42 (5.05) 0.75 0.59

Table 2: Association of the FGB –455 G/A genotypes with atherosclerotic changes of the LAD and abdominal aorta. Calculations based on the Mann-Whitney U-test and on the general ANOVA model with age, BMI, hypertension, diabetes and smoking as confounders.