| 
      *CAD was defined as clinically-significant 1- (n=937), 2- (n=471), or 3-vessel (n=349) disease of ≥70% stenosis; †Mild CAD was defined as maximum stenosis of 10-<70%, while no disease was defined as no lesion or luminal irregularities (n=1,606, including 152 mild CAD and 1,454 no-CAD)
        |  |  |  | CAD Patients* |  | Patients with Mild or No CAD† |  |  |  |  
        |  |  |  | rs1333049 genotype |  | rs1333049 genotype |  |  |  |  
        | Characteristic | GG | GC | CC |  | GG | GC | CC |  |  
        | Age (years) |  | 55 ± 9 | 55 ± 8 | 55 ± 8 |  | 68 ± 10 | 69 ± 9 | 69 ± 10 |  
        | Sex (male) |  | 78% | 78% | 80% |  | 57% | 50% | 53% |  
        | Diabetes |  | 0% | 0% | 0% |  | 0% | 0% | 0% |  
        | BMI (kg/m2) |  | 30 ± 6 | 29 ± 5 | 29 ± 6 |  | 28 ± 7 | 28 ± 6 | 28 ± 6 |  
        | Hypertension |  | 54% | 56% | 50% |  | 43% | 39% | 37% |  
        | Hyperlipidemia | 61% | 62% | 63% |  | 27% | 24% | 27% |  |  
        | Smoking |  | 25% | 29% | 25% |  | 11% | 10% | 9% |  
        | Family CHD History | 43% | 50% | 50% |  | 21% | 18% | 19% |  |  |