Alleles |
CC |
CT |
P value |
Rejection episodes |
+ (%) |
+ (%) |
|
0 (N=14)* |
3 (21.4) |
11 (78.6) |
<0.007 |
0-1(N=27) |
12 (44.4) |
15(55.6) |
NS |
1-2(N=31) |
23 (74.2) |
8 (25.8) |
<0.0001a |
2 (N=18) |
14 (77.8) |
4 (22.2) |
<0.002b |
2-3(N=29) |
23 (79.3) |
6 (20.7) |
<0.0001c |
≥4 (N=12)* |
10 (83.3) |
2 (16.7) |
<0.003d |
a: Odds Ratio (OR)=8.26 (95% CI; 2.3-30.9); b: OR= 12.25 (95% CI; 2.05-85.6);
c:OR=14.69 (95% CI; 3.5-66.35); d: OR=25.0 (95% CI; 2.16-484.8).
*: Individuals carrying CT alleles were compared in those with 0 rejection
episode vs. ≥4 grade 3R cellular rejection episodes within the first 6 months after
transplantation (p<0.005; OR=18.3; 95% CI; 1.92-247.02). |
