![]() |
Figure 1: Percent of CD8+ T cells from individuals vaccinated with LAIV or TIV expressing IL2, IFN-?, TNF-a, CD107a or Granzyme B (grzb). The T cell cultures were stimulated with monocyte-derived DC that had been loaded with a pool of influenza peptides as described in Materials and Methods. The box and whisker plot shows the median percent of CD8+ T cells expressing cytokine/antigen for each group within the box; the ends of the box representing the 1st and 3rd quartiles, and the minimum and maximum values. There were no statistical differences between the medians for each marker before and after vaccination with LAIV and TIV (Mann-Whitney, p>0.05). |