| Macroscopical signs of inflammation |
Score |
| 1-2 Swollen toes |
0.25 |
| 3-4 Swollen toes |
0.50 |
| Slightly swollen footpad or ankle |
0.50-0.75 |
| Swollen footpad or ankle |
1.00 |
| Swollen toes+slightly swollen footpad |
1.25 |
| Swollen toes+swollen footpad |
1.5 |
| Swollen footpad+swollen ankle |
2.00 |
Mice with collagen antibody induced arthritis (CAIA) or collagen induced arthritis
(CIA) were scored daily for signs of inflammation in their paws with a maximum
of 35 days. Scoring was performed according to the method outlined in the table,
resulting in a maximum arthritis score of 8 per animal. |
