Time Points SOD1 COX2 Collagen   24 hr ± + ± Control 7 days ± + ±   30 days ± + ±   24 hr ± + +± SiNPs-Cd 7 days ++ ++ +++   30 days ++± ++± ++±   24 hr ± ± +± CdCl2 7 days +± ++ ++±   30 days ++ ++± ++   24 hr ± + +± SiNPs 7 days + + ++±   30 days ± ± ++             SiNPS-Cd * * ** p Value CdCl2 * * *   SiNPs ns ns * Degree of staining intensity: from undetectable (-) to strong (+ + + +) p values calculated by Kruskal-Wallis test: (*) <0.05 ns=not statistically significant

Table 1: Expression of immunolabelling for SOD1, COX2 and Collagen (Type I) on a semiquantitative evaluation.