Group 1b (N=17)   Sd Min Max Cv CI OC1 22.17 11.12 4.1 42.9 50.16 16.45-27.90 CL1 383.92 230.20 18.8 852.3 59.96 265.53-502.31 Group 2b (N=161)   Sd Min Max Cv CI OC1 32.80 12.53 5.2 78.9 38.19 30.85-34.75 CL1 568.90 266.33 63.6 1290.0 46.81 527.44-610.36 Asymmetry and flattening values ranging from -.04 to .04 were not discussed Minimal (min) i maximal (max) biochemical markers of participants in Group 1b indicate that values are within the expected range. Larger values of the coefficient of variation (Cv) indicate that there is heterogeneity of Group 1b in terms of: OC1 (OC1) (50.16), CL1 (CL1) (59.96). Increased values of Skewness indicate that distribution is negatively asymmetric which means that distribution results curve tends toward larger values, i.e., there are larger values in comparison to normal distribution in: OC1 (OC1) (.11), CL1 (CL1) (.22). Negative values of Curtosis indicate that curve is flattened at: OC1 (OC1) (-1.12), CL1 (CL1) (-.35).Value distribution range mostly within normal distribution (p) at: OC1 (OC1) (.80), CL1 (CL1) (.73) Minimal (min) i maximal (max) biochemical markers of participants in Group 2b indicate that values are within the expected range. Larger values of the coefficient of variation (Cv) indicate that there is heterogeneity of Group 2b in terms of: OC1 (OC1) (38.19), CL1 (CL1) (46.81). Increased values of Skewness indicate that distribution is negatively asymmetric which means that distribution results curve tends toward larger values, i.e., there are larger values in comparison to normal distribution in: OC1 (OC1) (.33), CL1 (CL1) (.35). Negative values of Curtosis indicate that the curve is flattened at: OC1 (OC1) (.08). Value distribution range mostly within normal distribution (p) at: OC1 (OC1) (.66), CL1 (CL1) (.88)

Table 10: Central and dispersed parameters and asymmetry and flattening measures of laboratory parameters during the therapy, done in groups. (N=178).