Figure 3: (a) and (b) show the average T1Gd and ΔR1 of the two groups obtained with the three analysis methods: superficial region analysis provides significantly shortest T1Gd and highest ΔR1 in both the diseased and the control, followed by full-thickness analysis and deep region analysis; much larger standard deviations were observed with ΔR1 compared with T1Gd. (c) and (d) demonstrate the variation lines (line connecting the two average values of diseased and control groups) of the three analysis methods. With T1Gd the three lines are almost parallel to each other, indicating the three analysis methods are almost equally effective. With ΔR1, the line of superficial analysis is just slightly steeper compared to other two lines, but no significant difference was observed because of higher standard deviation.