Type of regulation

DU-145

Differentiated versus control

DU-145

Undifferentiated versus control

PC-3

Differentiated versus control

PC-3

Undifferentiated versus control

Repressed

14

141

190

1

No change

11568

11208

11267

11596

Increased

25

258

150

10

Table 3: Illumina protocol: The data generated from the Illumina Beadchip platform on DU-144 cells demonstrate a significant larger differential expression (399 reporters) in co-culture with undifferentiated osteoblast cells compared to the differentiated (35 reporters). This is in contrast to PC-3 cells where co-culture with differentiated osteoblasts dominates the differential expression with 340 reporters while there are only 11 in the case of undifferentiated.