Table 2

Category	p-value*	Number of genes#
Cell Death	4.74E-09 - 1.82E-01	206
Cellular Growth and Proliferation	1.38E-06 - 1.82E-01	221
Cell Cycle	2.46E-03 - 1.82E-01	90
DNA Replication, Recombination, and Repair	4.28E-03 - 1.82E-01	55
Cellular Development	5.94E-03 - 1.82E-01	144
Gene Expression	9.22E-03 - 1.82E-01	142
Cell-To-Cell Signaling and Interaction	2.71E-02 - 1.82E-01	39
Cell Morphology	3.26E-02 - 1.82E-01	95
Cellular Movement	3.26E-02 - 1.82E-01	63
Cellular Assembly and Organization	5.56E-02 - 1.82E-01	24
Carbohydrate Metabolism	8.21E-02 - 1.76E-01	21
Lipid Metabolism	8.21E-02 - 1.68E-01	32
Molecular Transport	8.21E-02 - 1.76E-01	33
Nuclic Acid Metabolism	8.21E-02 - 1.82E-01	4
Small Molecule Biochemistry	8.21E-02 - 1.82E-01	48
Antigen Presentation	9.25E-02 - 1.76E-01	29
Cellular Function and Maintenance	9.47E-02 - 1.76E-01	21
Cell Signaling	1.14E-01 - 1.76E-01	44
Amino Acid Metabolism	1.35E-01 - 1.76E-01	4
Vitamin and Mineral Metabolism	1.35E-01 - 1.35E-01	3
Protein Synthesis	1.82E-01 - 1.82E-01	27

*The ‘p-value’ was calculated using the right-tailed Fisher Exact Test and corrected for false discovery rate by the Benjamini-Hochberg method. Only those categories with a p value <0.05 are considered significant and therefore are presented. #The ‘number of genes’ represents the number of differentially expressed genes belonging to the specific IPA category in the Cr(VI) treated cells.

Table 2: IPA Classification of the Differentially Expressed Genes in the Cr(VI) treated Dermal Fibroblasts into Cellular and Molecular Functions Categories.