Category

p-value*

Number of Genes#

Apoptosis

4.74E-09 - 1.82E-01

170

Cell Death

1.53E-08 - 1.81E-01

188

Survival

4.71E-02 - 1.35E-01

61

Cell Viability

3.07E-02 - 1.82E-01

26

Anoikis

8.50E-02 - 1.82E-01

10


*The ‘p-value’ was calculated using the right-tailed Fisher Exact Test and corrected for false discovery rate by the Benjamini-Hochberg method. Only those categories with a p value <0.05 are considered significant and therefore are presented. #The ‘number of genes’ represents the number of differentially expressed genes belonging to the specific IPA category in the Cr(VI) treated cells.
Table 3: IPA Classification of the Differentially Expressed Genes in the Cr(VI) treated Dermal Fibroblasts into Categories Related to Cell Death Function.