Groups (area) NP (II) RN (I) MRN (I) RN (II) MRN (II) RN(I) <0.0001 - - - - MRN(I) <0.0001 0.9856 - - - RN(II) <0.0001 0.9999 0.9998 - - MRN(II) <0.0001 0.9999 1.0000 1.0000 - TN(II) <0.0001 0.9998 0.9998 0.9998 0.9009 Significance set at P<0.05

Table 1: P values calculated from multiple comparison of loss of c-MYC gene by MN-Heps on regenerative (RN), macroregenerative (MRN) and tumoral (TN) nodules from LC/HCV without (I) and with HCC (II) groups in relation to control group (III) - normal parenchyma (NP).