Mouse group

n

 

BW

 

Initial

Final

Carcass

L-C

6

17.9± 0.6

25.0±4.1

17.8±1.9

L-I

7

17.2 ± 1.4

24.7±4.9

17.2±3.6

L-II

7

17.4 ±0.8

24.4±3.9

16.2±3.2

DIO-C

11

17.8 ±1.1

35.5±8.4f

23.3±4.8

DIO-I

7

18.1± 0.8

34.9±9.7g

19.4±3.4

DIO-II

7

17.8 ±0.6

25.6±4.9b

17.8±3.2d

DIO-MT

3

17.4±1.2

22.1±3.7a,c

15.4±1.6e

Term definitions: BW: body weight (grams, g). DIO-MT: DIO-mice hosting mammary tumors. “a”: Net BW of DIO-MT (BW-DIO mice subtracting mammary tumor weights). Statistical significance: b = p≤ 0.01 (DIO-C vs DIO-II); c = p≤ 0.01 (DIO-C vs DIOMT); d = p≤ 0.02 (DIO-C vs DIO-II); e = p≤ 0.02 (DIO-C vs DIO-MT); f = p≤ 0.01 (L-C vs DIO-C); g = p≤ 0.04 (L-C vs DIO-I).
Table 1: Effects of leptin antagonist treatment on body weight of DMBA-mice.