| TSE |
Natural Hosts Reported |
Human Health Risk |
| Scrapie |
Sheep, Goats |
None Reported |
| Bovine Spongiform Encephalopathy (BSE) |
Cattle, transmits readily across species barriers |
High – Consumption of affected material |
| Chronic Wasting Disease (CWD) |
Wild and Farmed Deer, Elk, Moose |
None Reported |
| Transmissible Mink Encephalopathy (TME) |
Farmed Mink |
None Reported |
| Variant CreutzfeldJakob Disease (vCJD) |
Human (derived from BSE) |
High – transmission via blood products, Nosocomial, Consumption of BSE-contaminated food products |
| Creutzfeld-Jakob Disease |
Humans |
Sporadic, Genetic, Iatrogenic. High-transmission by exposure to contaminated brain material, Nosocomial. |
| Kuru |
Human |
Transmitted by ritualistic cannibalism |
| Fatal Familial Insomnia |
Human |
Autosomal Dominant,Pathogenic mutation with high penetrance |
| Gerstmann-Straussler- Sheinker disease |
Human |
Autosomal Dominant,Pathogenic mutation with high penetrance |
