Figure 3: Post-exposure sickness score against aerosolized RVFV challenge. Mice immunized with indicated vaccines (Figure 3A) or appropriate controls, live-attenuated MP12 vaccine, DNA plasmid with no insert (DNA control) and replicon expressing influenza HA (replicon control) (Figure 3B) were challenged with 1000 PFU of RVFV ZH501 and monitored for clinical symptoms associated with RVFV infection and mortality daily post-challenge. A two-way ANOVA with Bonferroni’s post-tests was used to determine the significance of sickness score data between different groups, which is denoted by asterisks; **P<0.01, *** P<0.001.