Figure 3: Regulatory networks showing clusters of differentially-regulated genes involved in cell signaling and apoptosis. Red-colored genes show significantly increased expression at all time points in B. anthracis treated cells, compared to the control cells (a color scale is at the bottom right corner). The uncolored nodes are network members that are not significantly regulated by the B. anthracis insult, as found in the present study. The nodes represent the genes or proteins; and the solid and dashed arrow-headed lines depict the direct and indirect interactions, respectively.