Analyte

Assay (spiking method)

Assay in serum

Conc.

%RSD

% Rec

%RSD

%Rec

µgmL-1

CAP

8

0.01

101

0.002

101

10

0.33

100.04

0.02

102

12

0.02

99.97

0.03

101

HCT

8

0.01

100.5

0.002

100.3

10

0.3

100.02

0.002

101.3

12

0.3

99.98

0.02

100.3

FRS

8

0.22

99.3

0.5

100.2

10

0.2

99.98

0.36

100.6

12

1.03

99

0.9

101.3


CAP: captopril; HCT: hydrochlorothiazide; FRS: furosemide
Table 3: Accuracy of the proposed method for captopril, hydrochlorothiazide and furosemide.