Figure 7: (A) Three-SNP multiple linear regression (MLR) models for natural log of hair melanin ratio’s across populations (training sample set). The horizontalaxis depicts all 3654 combinations (i.e., 29-choose-3) of significant SNPs in a three-SNP MLR model. The vertical-axis is the R2 value for each model (black curve or three-SNP R2 curve) and also the SNP function value for each SNP curve. The R2 curve inflection (i=162) is indicated by a vertical black line. The SNP curves of the three highest frequency SNPs at i=162 are indicated by colors (rs12913832 (HERC2), blue; rs1805007 (MC1R), orange ; rs16891982 (SLC45a2), red). (B) Bar plot of the SNPs that were present in all models from i=1 to i=162.