Table 4

Gene	SNP	40 significant SNPs (training sample)	45 SNPs (test sample)	40 Significant SNPs (test sample)	33 overlapping SNPs	29 significant SNPs (training and test samples)	Total hair melanin	Natural log of ratio of melanins	Skin reflectance (CIEL)	Eye Color
AMACR	rs13289		+	+					*
ASIP	rs2424984	+	+	+	+	+			*
ASIP	rs6058017	+
CYP4B1	rs1572603	+	+	+	+	+				*
DCT	rs1325611	+	+	+	+	+	*	*	*	*
DCT	rs1407995	+	+	+	+	+	*	*		*
GPR143	rs3044	+	+	+	+	+	*	*	*	*
HERC2	rs1129038		+	+			*	*	*	*
HERC2	rs12913832	+	+	+	+	+	*	*	*	*
HERC2	rs1667394		+	+			*	*	*	*
HERC2	rs916977		+	+			*	*	*	*
HPS3	rs2689234	+	+		+
HPS4	rs1894704	+
HPS4	rs3752589	+
HPS4	rs3752590	+	+		+
HPS4	rs739289	+	+	+	+	+				*
IRF4	rs12203592		+	+			*		*	*
MC1R	rs1805007	+	+	+	+	+		*
MC1R	rs1805008	+	+	+	+	+		*
MC1R	rs3212346	+	+	+	+	+	*		*
MC1R	rs3212355	+
MC1R	rs3212357	+
MLPH	rs2292885	+	+	+	+	+		*	*
MYO18A	rs11080078	+	+	+	+	+				*
MYO5A	rs1724630	+	+	+	+	+	*	*	*	*
MYO5A	rs2290332	+	+	+	+	+	*	*		*
MYO5A	rs752864	+	+	+	+	+	*
MYO7A	rs2276289	+	+	+	+	+	*		*	*
MYO7A	rs3737454	+	+	+	+	+			*	*
near ASIP	rs1015362		+	+				*	*
near KITLG	rs12821256		+	+			*
near SLC24A4	rs12896399		+	+			*	*	*
near TYRP1	rs1408799		+	+			*	*	*	*
OCA2	rs1037208	+	+	+	+	+			*
OCA2	rs10852218	+	+	+	+	+			*
OCA2	rs11638265	+	+	+	+	+	*	*	*	*
OCA2	rs1375164		+	+			*	*	*	*
OCA2	rs1800404	+	+	+	+	+	*	*	*	*
OCA2	rs1800407	+	+		+
OCA2	rs1800410	+
OCA2	rs1800411	+	+	+	+	+	*	*	*	*
OCA2	rs1800414	+
OCA2	rs1900758	+	+	+	+	+	*	*	*	*
OCA2	rs749846	+	+	+	+	+	*	*		*
SLC24A5	rs1426654	+	+	+	+	+	*	*	*	*
SLC45A2	rs16891982	+	+	+	+	+	*	*	*	*
SLC45A2	rs2287949	+	+	+	+	+	*		*	*
SLC45A2	rs26722	+	+	+	+	+	*	*	*	*
SLC45A2	rs40132	+	+		+
TPCN2	rs35264875		+
TYR	rs1393350		+	+			*	*	*	*

* Significant SNPs (test sample) by ANOVA (p<0.05)

Table 4: 52 SNPs within or close to 22 genes.