Cell Line Type Details of BRCA Gene Mutation GM00893 Normal None GM05423 Normal None GM13705 BRCA1 4-base pair deletion in exon 11 = truncated protein. GM14090 BRCA1 2-base pair deletion in exon 3 = truncated protein. GM16105 BRCA1 Base substitution in intron 8. GM14170 BRCA2 1-base pair deletion in exon 11 = frameshift mutation. GM14622 BRCA2 2-base pair deletion in exon 11 = frameshift mutation = truncated protein. GM14805 BRCA2 Base substitution in exon 7 = nonsense mutation. Table 1 provides a description of the B-Lymphoblastoid cell lines used in the study together with the information on the mono-allelic mutation in the BRCA1 and BRCA2 heterozygous cell lines

Table 1: Description of B-Lymphoblastoid cell lines used in study.