Ref. NO Cells Origin Target genes [40] MIN6 Mouse pancreatic βcell GPR40 [41] Jurkat Human acute T cell leukemia SS-A/Ro52 [42] C2C12 Mouse myoblast(differentiated) Bin1 [43] primary monocyte Human monocyte Caveolin-1 [44] primary cardiac myocyte Rat cardiac myocyte phospholamban [45] U937 Human leukemic monocyte cell Brap2 [46] K562 Human chronic myelogenous leukemia Bim [47] HUVEC Human umbilical vein endothelial cell TSAd [48] CMK6G3 Monkey ES cell Monkey ES cell (stably expresses EGFP) EGFP [49] primary monocyte Human monocyte Tollip, IRAK- [50] HuH-6, HuH-7, HepG2 Human hepatoblastoma cell Human hepatocecellular carcinoma cell β-catenin [51] J774 Mouse macrophage cell IL-13 Receptor α2 [52] MIN6 Mouse pancreatic β cell GPR40 [53] primary T cell Human peripheral blood Human CARMA1 [54] Primary calvarial osteoblasts Mouse calvarial osteoblasts OPG [55] primary mast cell Mouse bone marrow-derived GATA-1,GATA-2 [56] INS-１E, NIH-3T3 Rat β cell, Mouse embryonic fibroblast Sox6 [57] primary macrophage C3H mouse peritoneal resident Mcl-1 [58] primary granulosa cell Mouse granulosa cell Snap25 [59] primary granulosa cell Rat granulosa cell TACE/ADAM17 [60] BASMC Bovine aortic smooth muscle cell Bovine TE(tropoelastin) [61] U937 Human leukemic monocyte cell Human cathepsin G [62] A549, H1299,TE13, PCNA-1, MIAPaCa-2, Du-145, ME-180 Human carcinoma (lung, esophageal, pancreas, prostate, cervical) Ku80 [63] HMVEC-dLyNeo(LEC) Human neonatal dermal lymphatic microvascular endothelial cell TLR4 [64] U251MG, D54MG Human glioma(p53 mutated at codon 273) Human glioma(p53 wild type) Survivin, p53 [65] granulosa cell Mouse granulosa cell TLR2, TLR4 [66] granulosa cell Mouse granulosa cell Mkp3 [67] COLO201 Human colon cancer FKBP51 [68] alveolar type II epithelial cells Mouse alveolar type II epithelial cells Nedd4, Nedd4-2 [69] primary alveolar type2 cell mouse lung alveolar type2 cell LPCAT1 [70] Primary neonatal cardiac ventricular myocyte Rat primary neonatal cardiac ventricular myocyte TFAM,TFB2M [71] U937 Human leukemic monocyte cell VEGFA*1 [72] Mouse suprachiasmatic nucleus slice cultures Mouse suprachiasmatic nucleus Atf4 [73] Human alveolar epithelial type Ilike (ATI-like) cells Human alveolar epithelial Nrf2 [74] U937 Human leukemic monocyte cell PP2ACα [39] U937 Human leukemic monocyte cell Mk2 [75] Human alveolar epithelial type Ilike (ATI-like) cells Human alveolar epithelial Nrf2 [76] U937 Human leukemic monocyte cell PP2ACα [77] Artery smooth muscle cells Porcin e ROCK2, MLCK, ZIPL, RORα [78] primary cardiomyocytes Neonatal rat HMGB1 *1miRNA

Table 2: siRNA transfection studies using the HVJ-E (in vitro).