Particle dia.
Number of cells, mln.
NL/AM ratio
total Alveolar macrophages (АМ) Neutrophil leucocytes (NL)
- 2.53±0.36 2.06±0.29 0.30±0.05 0.15±0.03
10 nm 18.57±3.20 2.72±0.54 14.99±2.57 6.23±0.62
50 nm 26.37±5.12 5.05±0.93*●ϒ 20.65±4.37 4.42± 0.57*●ϒ
1 μm 4.06±0.44*● 1.81±0.24 1.93±0,28*● 1.32±0.27*●
«*» – designates values that are statistically significantly different from control value; «●» – same from the value for «10 nm» group; ϒ - same from «1 μm» (Р<0.05 by
Student’s t-test)
Table 1: Count of BALF cells 24 hours after intratracheal instillation of suspensions of magnetite particles (2 mg/ml) of various sizes to rats (X±s.e.).