Fullerene Derivative

A23187 + FD*

poly-L-lysine + FD*

Biotin

83.9 (±8.0)¥¥¥

no Inh

C70-OH

60.6 (±28.2)¥¥

16.41 (±10.5)¥

CCC

no Inh

no Inh

DMAE

41.1  (±12.9)¥

no Inh

Ethanolamine

52.3 (±3.9)¥¥¥

no Inh

Niacin

73.2 (±9.6)¥¥¥

no Inh

NSAID

no Inh

12.0 (±6.2)¥

PC4

94.1 (±14.2)¥¥

no Inh

Tetraglutamate

59.7 (±3.0)¥¥¥

48.3 (±1.86)¥¥¥

Tetrainositol

95.7 (±2.3)¥¥¥

72.4 (±6.7)¥¥¥

Tetraphosphate

39.3 (±14.3)¥

no Inh

Tetrapyridine

51.7 (±17.5)¥¥

no Inh

Tetrasulfonate

39.9 (±2.5)¥¥¥

no Inh

TGA 

93.7 (±4.6)¥¥¥

70.2 (±1.0)¥¥¥

TTA

98.7 (±3.6)¥¥¥

66.8 (±3.1)¥¥¥

* FD Treatment at 10 μg/mL.
¥¥¥ p value < 0.01 / ¥¥ p value < 0.02 / ¥ p value < 0.05
no Inh = no significant inhibition observed
Table 2: Mean % inhibition of TNF-α (±SD) in FD treated and untreated MC.