Formulation
C
max
[µg/mL] p* to Cntr
Ratio C
max
Form./Control
AUC
0-6h
[µg ∙ h/mL] p to Cntr
Ratio AUC
0-6h
Form./Control
Control
0.18 ± 0.02
-
0.97 ± 0.08
-
BR-DIM
0.22 ± 0.02 p=0.207
1.22
1.05 ± 0.05 p=0.429
1.08
F127-DIM
3.08 ± 0.17 p<0.0001
17.11
7.06 ± 0.93 p=0.0006
7.28
*- p-values calculated by two-tailed t-test
Table 1:
C
max
and AUC
0-6h
values calculated for the animals treated with Control (non-formulated crystalline DIM), BioResponse DIM (BR-DIM), and F127-DIM formulation (F127-DIM).