**Figure 4: Quantitative analysis of the effect of PEG length on the binding
affinity and selectivity of micellar formulations after FACS analysis in a cocultured
cell model.** (A) The percent of cells with associated micelles indicated
as the cell population shifted to the region with higher red fluorescence intensity
in the dot plot acquired by FACS analysis. (B) The binding affinity defined as
the percent of MCF-7 cells with associated micelles divided by the total MCF-7
cells tested; The binding selectivity defined as the percent of MCF-7 cells with
associated micelles divided by the percent of C166-GFP cells with associated
micelles (mean ± SD, n=9). |