Figure 6: Targetability and cytotoxicity of the optimized phage-micelle formulation. (A) Selective cell binding by the florescence microscopy. Bright field shows a co-culture of MCF-7 and C166-GFP cells. In the overlay image, green fluorescence shows the location of C166-GFP cells; red fluorescence shows rhodamine-labeled phage-micelles associated with cells. (B) Cytotoxicity of different formulations towards MCF-7 cells after 72 h treatment with MCF- 7-targeted phage-micelles and various controls, including free PCT in DMSO, PCT-loaded plain micelles, drug-free MCF-7-targeted phage-micelles. (* p <0.05, mean ± SD, n=6).