Figure 3: Wheel running indices (distance, duration, and speed) for male C57BL/6J mice at baseline, during injections, and during injections supplemented with either testosterone or 17-estradiol. White bars denote control mice (n=9) that received vehicle injections and empty silastic implants. Checkered bars denote experimentally treated mice (n=10) that received exemestane injections and silastic implants containing testosterone. Black bars denote experimentally treated mice (n=10) that received exemestane injections and silastic implants containing 17-estradiol.