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Figure 4:Effect of pH on the binding constant (Kb) of kanamycin A (panel A,
filled circles) and kanamycin B (panel B, filled circles) to ANT. Determined
Δn (Δ) is shown with the overall charge on aminoglycosides ([NH3
+]- open squares) and the total charge ([NH3 +]+Δn, open diamonds) at three different pH. |