Rabbit ID

Genetic background

Vaccine

Tumor size of pooled sites
(Mean GMD+SE)

Before therapy

After therapy

R1327 (C1)

Inbred

HPV16E7/82-90

3.17+0.38

3.29+0.73 a

R1367 (C2)

R1517 (C3)

Outbred

R1518 (C4)

 

R1364 (T1)

Inbred

CRPVE1/149-57

3.26+0.28

1.51+0.71 b

R1365 (T2)

R1515 (T3)

Outbred

R1516 (T4)

aP>0.05, bP<0.05, unpaired student t test vs. before therapy

Table 4: Therapeutic immunization after CRPVE8ATGko mutant infection in HLA-A2.1 transgenic rabbits with both EIII/JC inbred and outbred background.