Figure 5: Percent survival of immunized and infected mice. Mice were immunized with recombinant proteins or PBS and than infected with a lethal dose of 80,000 trypomastigotes and monitored daily for 42 days. The time course of survival is shown. The values plotted are the mean SD for four mice per group and are representative of two independent experiments with similar results. # or * indicates a statistically significant difference with p <0.01 or p <0.05, respectively, comparing immunized to non-immunized animals by Kaplan-Meier analysis.