Fed animals |
Mean of % inhibition in fed animals ( ±SD ) |
Results |
Cat 1 |
13.0 ±0.3 |
Positive |
Cat 2 (fed) |
16.2 ± 0.7 |
Positive |
Cat 3 (fed) |
10.0 ± 0.5 |
Positive |
Cat 4 (non fed) |
1.37 ± 0.07 |
Negative |
Cat 5 (non fed) |
1.63 ± 0.04 |
Negative |
The results of this experiment suggest that the feline anti-HIV-gp120 antibodies
were anti-anti-idiotypic antibodies, able to inhibit the binding of HIV-gp120 peptide
to anti-HIV-gp120 antibodies. The results showed statistically significant difference
between the means of % inhibition of fed and non-fed animals, p = 0.015. |