Figure 4: Cellularity of patients’ PBMCs stimulated with CH401MAP.
Cell ratio index of 3 patient groups (HER2 0, HER2 1+2+, and HER2 3+) and a healthy donor group (HD) in lymphoid gated PBMCs are shown. (a) HD, healthy donors (n=19); (b) HER2 0, patients with HER2 expression immunohistochemistry (IHC) score 0 (n=25). (c) HER2 1+2+, patients with HER2 expression IHC scores 1+ and 2+ (n=53). (d) HER2 3+, patients with HER2 expression IHC score 3+ (n=12). Open circles represent each patient’s cell ratio index. Solid bars represent mean values of each group. Significant differences between HD and each patient group are shown with * (p<0.05) and ** (p<0.001).