Groups |
IL-4 (pg/ml) |
IFN-γ (pg/ml) |
PBS |
56.1 ± 4.8 |
60.6 ± 0.8 |
C501 (pYAP97R1N) i.m. |
161.2 ± 6.8 |
147.0 ± 11.6 |
C501 (pYAP97R1N) orally |
172.4 ± 0.5 |
94.1 ± 8.3 |
168 strain i.m. |
119.9 ± 2.4 |
126.1 ± 2.0 |
168 strain orally |
67.8 ± 4.1 |
123.5 ± 5.0 |
Splenocytes were isolated 42 days after primary immunization and stimulated with
purified P97R1N proteins for 72 h to determine IFN- γ and IL-4 production in the
culture supernatants by ELISA. |