Company Unit of A/c Sales 2012 Sales from Vaccines Profit Before Tax Contribution of Vaccines to Op. Profit       Value % Value %   Sanofi Mio Euros 34947 3897 11.1 6337 18.1 10.1 GSK Mio Pounds 26431 3325 12.6 7635 28.9 14.0 Merck Mio US $ 47267 1631 3.4 6299 13.3 NA Pfizer Mio US $ 58986 4117 7.0 12080 20.5 NA Novartis Mio US $ 56673 1858 3.2 9618 17.0 -0.5 Source: Published Company Annual Reports. NA : Not Available

Table 1: Profitability of Major Companies in the Vaccine Business in 2012