Period

Parameters

Control
X ± SD

4-CPA 10 ppm
X ± SD

4-CPA 20 ppm
X ± SD

SUBACUTE

 

SOD U/g

2206.6 ± 17.2

2199.9 ± 11.5

2194.1 ± 20.9

GR U/g

1.0 ± 0.04

1.1 ± 0.1

1.0 ± 0.1

CAT U/g

357.7 ± 22.8

353.2 ± 30.5

327.0 ± 32.0

GSH-Px U/g

45.0 ± 2.9

26.4 ± 2.5*

34.3 ± 2.7*

GST U/g

8.7 ± 0.4

8.0 ± 0.9

9.5 ± 0.3

G6PD U/g

3.2 ± 0.4

2.5 ± 0.3*

2.4 ± 0.2*

GSH mg/g

25.5 ± 0.7

25.7 ± 0.7

11.3 ± 1.8*

MDA nmol/g

9.1 ± 0.5

19.8 ± 1.8*

30.6 ± 3.4*

 

 

 

 

 

SUBCHRONIC

 

SOD U/g

2260.7 ± 24.1

2256.1 ± 23.8

2251.0 ± 20.8

GR U/g

1.1 ± 0.08

0.4 ± 0.05*

0.3 ± 0.04*

CAT U/g

355.7 ± 17.5

341.4 ± 14.2

295.1 ± 29.4*

GSH-Px U/g

78.4 ± 2.4

72.1 ± 1.5*

66.6 ± 2.1*

GST U/g

9.2 ± 0.1

9.1 ± 0.5

9.0 ± 0.4

G6PD U/g

3.0 ± 0.1

2.6 ± 0.1*

2.3 ± 0.1*

GSH mg/g

24.0 ± 0.7

28.1 ± 0.5*

23.8 ± 0.4

MDA nmol/g

11.8 ± 0.9

62.7 ± 3.8*

66.6 ± 2.9*

Each value represents the Mean ± SD. * p<0.05
Table 10: Effects of 4-CPA 10-20 ppm on antioxidant defence systems and MDA contents in liver of rats at subacute and subchronic.