Period |
Parameters |
Control
X ± SD |
4-CPA 10 ppm
X ± SD |
4-CPA 20 ppm
X ± SD |
SUBACUTE |
SOD U/ml |
2204.1 ± 22.1 |
2184.7 ± 36.9 |
2162.6 ± 20.7* |
GR U/ml |
0.9 ± 0.03 |
1.0 ± 0.02* |
0.8 ± 0.07* |
CAT U/ml |
108.0 ± 5.8 |
88.3 ± 9.3* |
59.2 ± 9.7* |
GPx U/ml |
348.7 ± 13.8 |
215.5 ± 11.2* |
231.5 ± 9.3* |
GST U/ml |
4.4 ± 0.3 |
3.6 ± 0.2* |
2.4 ± 0.2* |
G6PD |
0.9 ± 0.01 |
1.0 ± 0.08* |
0.9 ± 0.06 |
GSH mg/dl |
17.0 ± 0.8 |
13.8 ± 0.8* |
10.8 ± 0.8* |
MDA nmol/ml |
10.0 ± 0.5 |
14.3 ± 1.0* |
21.4 ± 1.5* |
|
|
|
|
|
SUBCHRONIC |
SOD U/ml |
2278.5 ± 13.0 |
2258.7 ± 24.1 |
2263.5 ± 21.7 |
GR U/ml |
0.9 ± 0.1 |
0.7 ± 0.05 |
0.5 ± 0.08* |
CAT U/ml |
107.6 ± 17.7 |
160.3 ± 20.1* |
148.3 ± 26.3* |
GPx U/ml |
431.0 ± 11.3 |
377.9 ± 7.5* |
373.5 ± 8.3* |
GST U/ml |
4.1 ± 0.3 |
0.3 ± 0.05* |
0.9 ± 0.05* |
G6PD |
1.0 ± 0.05 |
1.1 ± 0.04 |
1.0 ± 0.07 |
GSH mg/dl |
18.3 ± 0.4 |
16.6 ± 0.4* |
16.7 ± 0.7* |
MDA nmol/ml |
9.1 ± 0.5 |
34.4 ± 2.1* |
49.5 ± 2.6* |
Each value represents the Mean ± SD. * p<0.05
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