pre

Day after HbV administration

1

3

7

14

PO2 (mmHg)

Ave. (range)

96.3±4.9 (90-101)

93.3±2.2 (90-95)

93.8±6.2 (87-100)

98.5±6.0 (92-106)

90.8±17.7 (66-107)

PCO2 (mmHg)

Ave. (range)

29.7±2.4 (27.1-32.9)

31.9±2.3 (29.4-34.9)

31.0±2.1 (28.0-32.8)

30.5±2.9 (26.3-32.9)

28.5±1.8 (26.3-30.6)

pH

Ave. (range)

7.36±0.09 (7.26-7.46)

7.44±0.07 (7.36-7.52)

7.47±0.02 (7.44-7.49)

7.44±0.02 (7.41-7.45)

7.38±0.08 (7.27-7.47)

Data are mean ± S.D. (n=4)
Table 3: Changes in arterial blood oxygen tension (PaO2), arterial blood carbon dioxide tension (PaCO2) and pH after hemoglobin-vesicle administration at a dose of 1400 mg Hb/kg in male cynomolgus monkeys.