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Table 2: Effectiveness and CYP metabolism of antibiotic agents used in the therapy of PD. References given in parentheses. “Aa” means Aggregatibacter actinomycetemcomitans, “Tf” Tannerella forsythensis and “Pg” Porphyromonas gingivalis. +: 10-fold increased, ++: 102-fold increased concentration of antibiotic in gingival fluid, expressed in multiples of in-vitro measured minimal inhibitory concentration [32]. |