Treatment (mg/kg, p.o) Relative organ weight on 45th day (gm/100 gm of body weight) M ± SEM
Liver Kidney Heart Spleen
Vehicle control 5.374 ± 0.104 1.223 ± 0.027 0.483 ± 0.029 0.304 ± 0.036
Pyridostigmine (20) 5.066 ± 0.082ns 1.174 ± 0.052ns 0.516 ± 0.090ns 0.272 ± 0.045ns
Pyridostigmine (30) 3.915 ± 0.040*** 1.104 ± 0.025ns 0.432 ± 0.053ns 0.202 ± 0.017ns
Pyridostigmine (45) 3.407 ± 0.282*** 1.101 ± 0.090ns 0.345 ± 0.055ns 0.194 ± 0.054ns
n=10. ***P<0.001 and ns=not significant when compared to respective control group
Table 3: Effect of daily oral administration of Pyridostigmine Bromide tablet up to 45 days on relative organ weight of rats.