Treatment (mg/kg, p.o) |
Relative organ weight on 45th day (gm/100 gm of body weight)
M ± SEM |
Liver |
Kidney |
Heart |
Spleen |
Vehicle control |
5.374 ± 0.104 |
1.223 ± 0.027 |
0.483 ± 0.029 |
0.304 ± 0.036 |
Pyridostigmine (20) |
5.066 ± 0.082ns |
1.174 ± 0.052ns |
0.516 ± 0.090ns |
0.272 ± 0.045ns |
Pyridostigmine (30) |
3.915 ± 0.040*** |
1.104 ± 0.025ns |
0.432 ± 0.053ns |
0.202 ± 0.017ns |
Pyridostigmine (45) |
3.407 ± 0.282*** |
1.101 ± 0.090ns |
0.345 ± 0.055ns |
0.194 ± 0.054ns |
|
n=10. ***P<0.001 and ns=not significant when compared to respective control group |
Table 3: Effect of daily oral administration of Pyridostigmine Bromide tablet up to 45 days on relative organ weight of rats. |