Methyl Paraben (MP) Ethyl Paraben (EP) Propyl Paraben (PP) Butyl Paraben BP) 17-•-Estradiol E2 Titanium Dioxyde Indigotine Ponceau 4R 48 +/- 18 mg.L-1 (3.08*10-4 M) 7.8 +/- 2 mg.L-1 (4.73*10-5 M) 1.32 mg.L-1 +/- 80µg.L-1 (7.21*10-6 M) 504 +/- 15 µg.L-1 (2.59*10-6 M) 103 +/- 22ng.L-1) (3.77*10-10 M) 500 +/- 2mg.L-1) (6.5*10-3 M) 471 +/- 15mg.L-1) (1.8*10-3 M) 403 +/- 8 mg.L-1) (2.4*10-3 M)

Table 2: EC50 of 17-β-Estradiol and food additives compounds in distilled water samples obtained in YES test. (EC50 values, defined as the concentration where transcriptional response reaches 50% of its value at saturating concentration of ligand, were calculated from doseresponse assays, using 8 concentrations for parabens and food dyes and 10 concentrations for 17β-estradiol).