Histological parameters

Group

Infarct size (percent)

Scar thickness (mm)

Expansion index*

Akinesis &  dyskinesis (%)

 

hESC-CM

28.7 ± 5.5

1.3 ± 0.21

0.27 ± 0.11

8.96 ± 1.9

MSC+CM

35.7 ± 4.1

1.52 ± 0.28

0.31 ± 0.08

8.37 ± 1.67

HO-1 MSC+CM

30.8 ± 4.2

1.25 ± 0.14

0.36 ± 0.07

4.57 ± 1.00

saline

42.5 ± 2.8

0.71 ± 0.04

0.71 ± 0.05

10.73 ± 1.76

 

p value

 

0.166

 

0.091

 

0.0039

0.056

*For expansion index, there was a significant group effect by ANOVA (p=0.0039). Tukey's test showed that the expansion index was significantly higher in the control group versus each of the 3 cell-treated groups (p < 0.05).
Table 2: Infarct Size and Cardiac Function Four Weeks After Stem Cell-Based Therapy.