MicroRNAs(miRNAs)

 

Oncogenic/Tumor Suppressor

 

Targets

 

miR-155

 

Oncogenic

 

TP53INPI

 

miR-21

 

Oncogenic

 

Ras, Notch, PDCD4, TIMP3

 

miR-221

 

Oncogenic

 

CDKNIB/p27, CDKNIC/p57

 

Let-7 family

 

Tumor Suppressor

 

KRAS, EMT

 

miR-200 family

 

Tumor Suppressor

 

ZEB1, PTEN

 

miR-34a/b/c

 

Tumor Suppressor

 

P53, Bcl-2, Notch

Table 1: Oncogenic or Tumor Suppressive microRNAs and their Targets.