Central

Peripheral

Prefrontal cortex

Pre-ganglionic autonomic neurons

Hippocampus

Post-ganglionic autonomic neurons

Primary Dorsal horn afferents

Vagal neurons

Nucleus Accumbens

Dorsal root ganglia neurons

Area Postrema

C-fiber nociceptive afferents

Limbic System

Other nociceptive afferents

Table 2: 5-HT3 receptor locations.