Adult onset asthma

Stratified model

Joint model

Characteristics

Yes
(N=257)

No
( N=3151 )

Adj. RR 95% (CI) Adj. RR 95% (CI)

Physically active and
age at menarche

 
  
  Yes, >11 years
  199 (78.97)   2576 (85.98)   Referent   Referent   Referent   Referent
     Yes, ≤11 years 53 (21.03) 420 (14.02) 1.6 (1.19,2.15) 1.58 (1.18,2.13)
     No, >11 years 7 (77.78) 173 (84.80) Referent Referent 0.56 (0.26,1.18)
     No, ≤11 years 2 (22.22) 31 (15.20) 2.21 (0.51,9.59) 0.95 (0.24,3.65)

P-value for interaction

          0.943

Physically active and
menstrual regularity

 
  
  Yes, regular menses
212 (86.18) 2556 (85.31) Referent Referent Referent Referent
Yes, irregular menses 34 (13.82) 440 (14.69) Referent (0.65, 1.32) 0.93 (0.65, 1.32)
     No, regular menses 2 (22.22) 28 (13.73) Referent Referent 0.52 (0.25,1.10)
     No, irregular menses 7 (77.78) 176 (86.27) 1.11 (0.22,5.67) 0.89 (0.23,3.41)

P-value for interaction

          0.668

Physically active  and
 usual cycle length

     Yes,<36 days 7 (77.78) 186 (91.63) Referent   Referent   Referent Referent
     Yes, ≥36days 2 (22.2) 17 (8.37) 2.51 (0.58, 10.77) 2.83 (0.63,12.68)
     No, <36days 224 (91.06) 2758 (92.55) Referent Referent 2.80 (0.95, 4.18)
     No, ≥36 days 22 (8.94) 222 (7.45) 1.16 (0.76,1.78) 2.33 (1.01,5.36)

P-value for interaction

          0.262

Adjusted for age, race/ethnicity, BMI at age 18, educational status, smoking, parity, history of diabetes and history of hypertension , * physical activity for teen years (13-17) years

Table 4: Interaction of age at menarche and menstrual characteristics with physical activity on adult onset asthma.