Table 1

Genotype of females mated with stud male	Total number of females examined	Number of females give birth at term	Total number of pups born	Average number of pups/litter mean ± s.d.v.
Control*	11	11	98	8.91 ± 3.11
Hoxa10^-/-**	8	2	2	0.29 ± 0.46***
Hoxa10^-/-; Rag1^-/-	6	1	1	0.17 ± 0.38***
One or two adult females were housed with stud males. The date on which a vaginal plug observed was documented and considered 0.5 dpc. The number of pups born 18-20 days later was also documented. Control group included 1 wild-type, 3 Hoxa10^+/^-, 2 Rag1^-/-, 3 Hoxa10^+/^-;Rag1^+/^- and 2 Hoxa10^+/^-;Rag1^-/-* mice. **Hoxa10^-/- group included 6 Hoxa10^-/- and 2 Hoxa10^-/-;Rag1^+/^- mice. *** denotes P<0.0001 compared to control.

Table 1: Reproductive fecundity in control, Hoxa10^-/- and Hoxa10^-/-;Rag1^-/- females.