Figure 3b: Entropy of distribution of DX in the human genome (build #18) for different choices of W (=5Kbp, 50Kbp and 100Kbp) and reference (TSS and Body) for nearest gene assignment criterion (K=1). Higher entropy may mean higher bias in the analysis. It shows that low entropy of TSS reference with W=5kbp implies lowest bias and the entropy (and hence the bias) increases with increasing window size. For body reference, the entropy is high and remains almost same irrespective of the choice of W which is indicative of the large bias for studies involving body reference even for smaller W.