Arrowheads show cannulae placements and pyramidal cells populations in CA1 layer under histological examination Line is 300 μ

Figure 5: Verifying of lesion effect of colchicine (8μg/rat, intra-CA1) in rats’ CA1 layer cells (Figure 5A). The rats were injected colchicine (8 μg/ratl, intra- CA1) once a week before of verification Control slices (Figure 5B) were obtained from normal vehicle (0.9% physiological saline) injected group(1 μl/rat, intra-CA1) As data shows the alkaloid (8 μg/ratl, intra-CA1) induced a significant lesion effect in CA1 layer cells of the experimental animals.