| Male |
Control |
60mg/kg/day |
200mg/kg/day |
600mg/kg/day |
| Terminal body weights (g) |
419±25 |
421±30 |
412±25 |
371±22** |
| Kidneys (g) |
2.81±0.23 |
2.86±0.25 |
2.79±0.16 |
2.87±0.17 |
| (%) |
0.66±0.03 |
0.67±0.04 |
0.67±0.03 |
0.77±0.04** |
| Brain (g) |
2.09±0.06 |
2.07±0.08 |
2.03±0.07 |
2.07±0.10 |
| (%) |
0.49±0.03 |
0.49±0.04 |
0.49±0.03 |
0.55±0.03** |
| Female |
Control |
60mg/kg/day |
200mg/kg/day |
600mg/kg/day |
| Terminal body weights (g) |
276±19 |
275±26 |
272±19 |
252±17* |
| Brain (g) |
1.92±0.05 |
1.90±0.09 |
1.94±0.10 |
1.94±0.07 |
| (%) |
0.67±0.04 |
0.67±0.06 |
0.69±0.04 |
0.76±0.05** |
* Significantly different from control at P<0.05.
** Significantly different from control at P<0.01.
%: organ weight as a percentage of body weight |
