|
Parameter |
Group I |
Group II |
Group III |
Group IV |
Group V |
Group VI |
Group VII |
| after 1 month |
2-4 months |
4-6 months |
6-8 months |
8-10 months |
10-12 months |
>12 moths |
| Cylosporine dosage (mg/kg)
Mean ± SD |
2.2 ± 0.8 |
2.4 ± 1.6 |
2.5 ± 1.6 |
2.6 ± 0.7 |
2.5 ± 0.7 |
2.5 ± 0.9 |
2.2 ± 0.9 |
| Cylosporine trough level (ng/ml)
Mean ± SD |
188.9 ± 112.9 |
180.3 ±120.9 |
180.9 ± 97.7 |
166.6 ± 82.4 |
187.7 ± 75.6 |
176.5 ± 79.1 |
170.3 ± 91.3 |
| Cylosporine peak level (ng/ml)
Mean ± SD |
841.1 ± 492.8 |
819.6 ± 339.8 |
756.3 ± 367.9 |
809.4 ± 317.7 |
867.6 ± 331.8 |
697.1 ± 290.9 |
762.4 ± 492.7 |
| Serum creatinine (mg/dl)
Mean ± SD |
1.3 ± 0.3 |
1.2 ± 0.8 |
1.1 ± 0.8 |
1.5 ± 0.9 |
1.5 ± 0.8 |
1.4 ± 1.2 |
1.4 ± 0.9 |
| Glomerular filtration rate (mL/min)
Mean ± SD |
94.5 ± 38.9 |
80.8 ± 37.3 |
81.1 ± 41.2 |
87.4 ± 66.9 |
95.4 ± 88.1 |
96.8 ± 47.5 |
96.9 ± 44.8 |
| Blood urea-nitrogen level
Mean ± SD |
35.26 ± 22.9 |
48.17 ± 35.7 |
50.4 ± 35.3 |
47.5 ± 37.8 |
52.1 ± 31.9 |
46.1 ± 34.7 |
38.6 ± 32.1 |
| Blood urea level
Mean ± SD |
32.6 ± 27.4 |
35.1 ± 39.5 |
46.5 ± 47.6 |
29.4 ± 35.3 |
26.6 ± 36.6 |
22.5 ± 11.2 |
33.4 ± 4 |
| Serum Glutamic Pyruvic Transaminase (IU/L) Mean ± SD |
32.9 ± 15.1 |
34.7 ± 17.7 |
35.3 ± 17.5 |
39.1 ± 20.4 |
33.1 ± 14.1 |
33.7 ± 14.6 |
29.9 ± 13.9 |
| Serum Glutamic Oxaloacetic Transaminase (IU/L) Mean ± SD |
20.2 ± 9.1 |
20.9 ± 15.2 |
21.1 ± 12.8 |
24.7 ± 18.7 |
25.1 ± 17.3 |
21.9 ± 13.1 |
21.7 ± 16.8 |
| Serum Albumin Level (mg/dl) Mean ± SD |
6.8 ± 3.4 |
4.4 ± 2.3 |
3.4 ± 0.6 |
3.4 ± 0.8 |
3.3 ± 0.5 |
3.8 ± 3.2 |
3.6 ± 0.6 |
