| Species |
Duration (weeks) |
Recovery (Weeks) |
Dosing Regimen |
N (sex/group) |
Doses (mg/kg) |
| Rat |
2 |
None |
Daily |
5 |
0, 50, 300, 1200 |
| |
4 |
4 |
Daily |
10 |
0, 15, 50, 150 |
| |
12 |
None |
Daily |
10 |
0, 50, 150, 250 |
| |
12 |
None |
2 weeks on 2 weeks off |
10 |
0, 50, 150, 250 |
| |
8 |
6 |
Daily |
10 (control)
35 (treated) |
0, 250 |
| |
26 |
None |
Daily |
15 |
0, 50, 150, 250 |
| Dog |
4 |
4 |
Daily |
3 |
0, 50, 250, 500 |
| |
4 |
None |
Daily |
3 |
0, 2, 8, 20 |
| |
26 |
None |
Daily |
4 |
0, 8, 20, 60 |
|
